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>> October 2003 - The influence of lubricants on the tableting and disintegration time of tablets made of lactose-starch-blends or of STARLAC

Eugen Schwarz (1) , Olaf Haeusler (2) and Vera Fichtner (1)
(1) Meggle GmbH, 83512 Wasserburg, Germany
(2) Roquette Feres, 62080 Lestrem, France

Introduction
Starlac® is a new compound obtained via spray-agglomeration of 15% maize starch and 85% lactose monohydrate. It has been developed to offer a well-adapted material for the direct compression with higher performance in tableting compared to the simple blend of its components. The concept of Starlac® includes the optimization of its disintegration properties. It was therefore of interest to study the influence of several different lubricants on the disintegration time of systems based on starch and lactose monohydrate.

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